gaps 2009

Artists: Herwig Turk, Paulo Pereira, Johannes Hoffmann

rope, epoxy, boat color

Dimension: approximately 370 x 230 x 5 cm

Connexin 43 is a membrane protein. Connexins participate in the formation of gap-junctions, which are channels that cross the cell membranes and allow the passage of nutrients and small signalling molecules between two adjoining cells, thus ensuring intercellular communication. Intercellular communication, through gap-junctions, is vital to ensure the proper function of a number of tissues and organs, including the coordination of heart beat or the synchronization of uterine contractions during labor.

Steve Catarino is investigating the mechanisms that regulate degradation of connexin 43. Steve drew some models to help him to understand specific aspects of his hypothesis, giving shape to a number of concepts and indirect experimental observations.

Gaps is the 3D reproduction of a model drawn by Steve Catarino to illustrate the interaction between two adjacent cells.